Gudmundur H Gudmundsson Selected Research

Cathelicidins

1/2018	Immune responses in the treatment of drug-sensitive pulmonary tuberculosis with phenylbutyrate and vitamin D3 as host directed therapy.
1/2017	Treatment with Entinostat Heals Experimental Cholera by Affecting Physical and Chemical Barrier Functions of Intestinal Epithelia.
2/2016	Cathelicidins positively regulate pancreatic β-cell functions.
1/2015	Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing of Mycobacterium tuberculosis in human macrophages.
1/2014	Label-free quantitative mass spectrometry reveals novel pathways involved in LL-37 expression.
11/2013	Treatment with phenylbutyrate in a pre-clinical trial reduces diarrhea due to enteropathogenic Escherichia coli: link to cathelicidin induction.
4/2013	Oral intake of phenylbutyrate with or without vitamin D3 upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis.
5/2012	Efficacy of sodium butyrate adjunct therapy in shigellosis: a randomized, double-blind, placebo-controlled clinical trial.
1/2011	Phenylbutyrate counteracts Shigella mediated downregulation of cathelicidin in rabbit lung and intestinal epithelia: a potential therapeutic strategy.
12/2009	Phenylbutyrate induces antimicrobial peptide expression.

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Gudmundur H Gudmundsson Research Topics

Disease

17	Infections 01/2020 - 07/2005
5	Bacillary Dysentery (Shigellosis) 01/2017 - 06/2006
3	Muscle Cramp (Cramp) 02/2016 - 06/2006
3	Inflammation (Inflammations) 11/2013 - 06/2006
2	Pulmonary Tuberculosis 01/2018 - 01/2015
2	Diarrhea 07/2014 - 11/2013
2	Bacterial Infections (Bacterial Infection) 12/2009 - 06/2006
1	Ventilator-Induced Lung Injury 01/2020
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2020
1	Critical Illness (Critically Ill) 01/2019
1	Edema (Dropsy) 01/2018
1	Pancreatitis 01/2018
1	Whooping Cough (Pertussis) 01/2018
1	Cholera 01/2017
1	Coinfection 02/2016
1	Insulinoma 02/2016
1	Tuberculosis (Tuberculoses) 04/2013
1	Suppuration 05/2012
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2011
1	Communicable Diseases (Infectious Diseases) 01/2011
1	Acidosis 12/2006
1	Meningococcal Infections 12/2006
1	Atherosclerosis 07/2006
1	Atherosclerotic Plaque (Atheroma) 07/2006
1	Body Weight (Weight, Body) 06/2006
1	Sepsis (Septicemia) 02/2005
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2003

Drug/Important Bio-Agent (IBA)

14	CathelicidinsIBA 01/2018 - 06/2006
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 06/2006
7	Antimicrobial PeptidesIBA 01/2017 - 02/2005
5	Pharmaceutical PreparationsIBA 01/2020 - 12/2009
3	Cholecalciferol (Vitamin D3)FDA Link 01/2018 - 04/2013
3	Butyrates (Butyrate)IBA 02/2016 - 06/2006
3	Proteins (Proteins, Gene)FDA Link 02/2016 - 08/2008
2	Butyric Acid (Butanoic Acid)IBA 01/2017 - 05/2012
2	Adenosine Monophosphate (AMP)IBA 05/2014 - 12/2009
2	Peptides (Polypeptides)IBA 06/2006 - 07/2005
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2020
1	Virulence Factors (Pathogenicity Factors)IBA 01/2018
1	Amylases FDA Link 01/2018
1	Hemolysin Proteins (Hemolysins)IBA 01/2018
1	Lactose FDA LinkGeneric 01/2018
1	Peroxidase (Myeloperoxidase)IBA 01/2018
1	Adenylate Cyclase ToxinIBA 01/2018
1	zonulinIBA 01/2017
1	entinostat (MS 275)IBA 01/2017
1	AcidsIBA 02/2016
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 02/2016
1	SteroidsIBA 02/2016
1	Blood Glucose (Blood Sugar)IBA 02/2016
1	Dinoprostone (PGE2)FDA Link 02/2016
1	CaspasesIBA 02/2016
1	ErbB Receptors (EGF Receptor)IBA 02/2016
1	Glucose (Dextrose)FDA LinkGeneric 02/2016
1	Messenger RNA (mRNA)IBA 01/2015
1	Interleukin-8 (Interleukin 8)IBA 05/2012
1	Saline SolutionIBA 05/2012
1	DefensinsIBA 01/2011
1	4-phenylbutyric acid (Buphenyl)FDA Link 01/2011
1	CarbonatesIBA 12/2006
1	ChemokinesIBA 07/2006
1	SaltsIBA 02/2005
1	Granzymes (Granzyme)IBA 01/2003

Therapy/Procedure

9	Therapeutics 01/2020 - 05/2012
2	Artificial Respiration (Mechanical Ventilation) 01/2020 - 01/2019
1	Aftercare (After-Treatment) 01/2017